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Role of the Microbiome and Its Metabolites in Primary Sjögren's Syndrome.

Microorganisms · 2025 · PMC12472975 · PMID 41011312

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Notably, butyrate and propionate levels were significantly reduced in pSS patients, and although acetate levels did not reach statistical significance, its potential biological relevance cannot be ruled out due to the shared receptor-binding mechanisms among SCFAs.

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