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Real-World Prescribing Patterns and Treatment Continuation of Amitriptyline Monotherapy and Aripiprazole Augmentation for Medically Unexplained Oral Symptoms/Syndromes in Japan.

Pharmaceuticals (Basel) · 2025 · PMC12473115 · PMID 41011153

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showed a trendno p-value reported
Observations from the aripiprazole combination group showed a trend towards a relatively lower treatment discontinuation hazard in the dosage range of 1.7–1.8 mg/day, but this is merely an observed association, suggesting that escalation beyond this dosage may not necessarily contribute to treatment continuation.

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