The results showed a trend towards higher anxiety levels in Gtf2i -KO mice, indicated by their spending less time in the open arms compared to controls (Fig. 4C , mean control 249.1 ± 19.62 s, mean Gtf2i -KO 200.3 ± 16.59 s).
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Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements.
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