Comparison of imaging based single-cell resolution spatial transcriptomics profiling platforms using formalin-fixed paraffin-embedded tumor samples.

Nat Commun · 2025 · PMC12474935 · PMID 41006245

Europe PMC DOI

hedged sentence

0.3100

closest p · 6.2× alpha

0.3100

boldest claim

The sentences

showed a trendp = 0.31not close (p > 0.1)

While CosMx had significant differences between percentage of cells based on biological cell size differences ( p = 0.023), Xenium-UM and Xenium-MM also showed a trend towards a higher percentage of cells with gene pairs of bigger biological differences ( p = 0.31).

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