Variation of VP2 stoichiometry and deamidation of VP1 during production and their impacts on the transduction efficiency of AAV vectors.

Mol Ther Methods Clin Dev · 2025 · PMC12475848 · PMID 41020267

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a negative trendno p-value reported

Most importantly, among these QAs, the stoichiometric ratio of VP2 had a significant positive correlation and deamidation in VP1 had a negative trend/correlation with the transduction efficiency.

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