Human PXR Signaling Exacerbates Ethanol-induced Liver Injury in Females: Evidence From Mouse Models and Human Alcohol-associated Liver Disease Cohorts.

Cell Mol Gastroenterol Hepatol · 2025 · PMC12478072 · PMID 40681042

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did not reach statistical significanceno p-value reported

A similar trend was observed with glucose-regulated protein 78 (GRP78) protein, although the decrease in hPXR mice (2.9-fold in males and 2.6-fold in females) did not reach statistical significance ( Figure 7 S and T ).

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