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NAT10 regulates tumor progression and immune microenvironment in pancreatic ductal adenocarcinoma via the N4-acetylated LAMB3-mediated FAK/ERK pathway.

Cancer Commun (Lond) · 2025 · PMC12479129 · PMID 40540648

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Survival analysis based on TCGA‐PAAD data indicated that high NAT10 expression was significantly associated with poor progression‐free survival (PFS; HR = 1.600, P = 0.032), although a similar trend was observed for overall survival (OS; HR = 1.500, P = 0.076), the association did not reach statistical significance (Figure 1D ).

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