Comparative Analysis of Circulating and Synovial Immune Cells in Early Untreated Rheumatoid Arthritis and Their Relationship With Molecular Pathology and Disease Outcomes.

When comparing immune cell signatures in matched PB and synovial samples, although no significant correlations were found, most cells showed a clear trend toward negative correlations, which suggests the same cell types might have opposing trends in the two compartments (Figure 3B ).

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