A systematic review of Perinatal Antibiotic Stewardship - where we are, where to go?

J Perinatol · 2025 · PMC12479340 · PMID 39833335

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

a strong trendno p-value reported

Around half of the studies analyzed were published between 2014 and 2019 and their number doubled from 2020 to 2022, underlining a strong trend.

also in 5,725 other papers

highly significantno p-value reported

As an example, the prospective, multicenter randomised controlled intervention trial NeoPInS analyzing a procalcitonin-guided algorithm to safely shorten antibiotic therapy in a cohort of more than 1’700 neonates with suspected EOS reported a highly significant result for superiority (reduction of antibiotics), but failed to prove non-inferiority [ 55 ].

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.