Intravenous thrombolysis before percutaneous coronary intervention in patients with non-ST-elevation acute coronary syndrome and acute ischaemic stroke: a subanalysis of the PRAISE study.

Open Heart · 2025 · PMC12481274 · PMID 41022535

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0600

boldest claim

The sentences

just failed to reach statistical significancep=0.05actually significant

In regression analysis, IVT before PCI was associated with an 8.5-fold higher odds of achieving TIMI grade 3 flow; however, this association just failed to reach statistical significance (aOR=8.5, 95% CI (0.9 to 75.3); p=0.05).

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did not reach statistical significancep=0.06so close (0.05 < p ≤ 0.1)

Although TMP grade 3 perfusion was numerically four times more common after IVT (n=2 (5%) vs n=6 (21%)), the difference did not reach statistical significance (p=0.06).

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