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Ursodeoxycholic acid acts as an ileal FXR agonist in male mice with hepatic deficiency of FXR.

eGastroenterology · 2025 · PMC12481312 · PMID 41036243

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showed a trendno p-value reported
Supplementation of UDCA showed a trend towards increased UDCA and tauroursodeoxycholic acid (TUDCA) levels in serum, liver and intestine, although the male mice displayed more than twice the amount of these bile acids compared with the female mice.

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