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Left Main Disease: The Last Frontier for Medical Therapy in Stable Coronary Artery Disease?

Eur Cardiol · 2025 · PMC12481371 · PMID 41036022

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a strong trendno p-value reported
22 Despite the effect of DAPT, however, meta-analyses have revealed a strong trend of higher stroke rates after PCI versus OMT. 18 While the absolute stroke risk is rather small, its clinical impact is substantial given the potential for disabling neurologic impairment, and such risk should be discussed openly and transparently with patients before PCI.

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