Overexpression of <i>DDR1</i> contributes to gastric cancer progression by inhibiting the Hippo pathway.

There was a clear trend showing that nuclear YAP was higher in the DDR1 high (score = 2, 3) than in the DDR1 low (score = 0, 1) group (median: 0.3 vs. 0.8; mean: 0.52 vs. 0.71), while the difference in cytoplasmic YAP between the two groups was only marginal (median: 0.2 vs. 0.4; mean: 0.46 vs. 0.55; Fig. 4G ), suggesting that in DDR1 -overexpressing GC cells, YAP tends to translocate into the nucleus ( Supplementary Fig. 5 , available online).

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