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A Novel Model of Cardiac Remodeling by a Minimally Invasive Aortic Regurgitation Surgery in Mice.

JACC Basic Transl Sci · 2025 · PMC12481893 · PMID 40956257

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Because regurgitation persisted until postoperative week 10, the LVID further expanded, while the wall thickness did not continue to increase and even showed a trend toward thinning compared with the state in week 4, resulting in an additional increase in systolic wall stress and deterioration of cardiac function.

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