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Intravenous combined with nebulized polymyxin B may be effective in treating carbapenem-resistant gram-negative bacilli hospital-acquired pneumonia: a retrospective cohort study.

Eur J Clin Microbiol Infect Dis · 2025 · PMC12484255 · PMID 40632377

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[ 26 ] demonstrated better microbial clearance and reduced mortality in VAP patients with multidrug-resistant Klebsiella pneumoniae when treated with both intravenous and nebulized polymyxin B compared to intravenous polymyxin B alone, but these improvements did not reach statistical significance.

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