Forward and reverse genomic screens enhance the understanding of phenotypic variation in a large Chinese rhesus macaque cohort.

Notably, ANO10 (c.203-2 AG > G) heterozygous carriers also exhibited a nominally significant reduction in full-arm length (Mann–Whitney U test, p- value = 0.0139, Fig. 3d ), although the association test ( p- value = 4.12 × 10 −5 ) did not surpass the level of significance required by Bonferroni correction, likely because the correction approach is highly conservative and would tend to “overcorrect” the variants in the context of a mild or small effect 48 .

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