KCC2 enhancers normalize reflex responses and improve locomotor function after chronic spinal cord injury.

J Physiol · 2025 · PMC12487610 · PMID 40906931

Europe PMC DOI

hedged sentences

0.1025

closest p · 2.0× alpha

0.3728

boldest claim

The sentences

failed to reach significanceP = 0.1025not close (p > 0.1)

SCI pre‐CLP290 0.496 ± 0.209); however, this increase failed to reach significance ( t 10.3 = 2.418, P = 0.1025).

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did not reach statistical significanceP = 0.3728not close (p > 0.1)

There was a slight decrease in slope after administering CLP290, with slope values returning close to zero (0.006 ± 0.008; t 5 = 0.794, P = 0.4633), but it did not reach statistical significance compared to SCI ( t 5 = −1.567, P = 0.3728).

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