Chapter 3. Impact of estrogens on hemostasis.

Front Endocrinol (Lausanne) · 2025 · PMC12488444 · PMID 41048432

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did not reach statistical significanceno p-value reported

While most individual studies did not reach statistical significance, the pooled analysis showed a statistically significant 33% lower risk of VTE in users of natural E 2 -based COCs compared to synthetic EE-based COCs (pooled OR, 0.67; 95% CI, 0.51–0.87).

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