Comorbidity burden in elderly high-grade glioma patients: impact on radiotherapy outcomes.

BMC Cancer · 2025 · PMC12490160 · PMID 41039275

Europe PMC DOI

hedged sentences

0.1920

closest p · 3.8× alpha

0.2300

boldest claim

The sentences

a nonsignificant trendp = 0.192not close (p > 0.1)

Among patients with greater comorbidities (ACCI ≥6), hypofractionation was associated with a nonsignificant trend toward improved PFS (HR: 0.68, 95% CI: 0.38-1.21, p = 0.192).

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showed a trendp = 0.23not close (p > 0.1)

In the ACCI ≥ 6 group, although not statistically significant, patients receiving concurrent hRT with TMZ showed a trend toward a better OS than did those receiving Stupp (HR = 0.51, 95% CI: 0.17–1.53, p = 0.23).

also in 53,322 other papers

borderline significanceno p-value reported

In these models, the ACCI approached borderline significance but remained nonsignificant overall.

also in 7,017 other papers

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