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Cortical astrocyte histamine-1-receptors regulate intracellular calcium and extracellular adenosine dynamics across sleep and wake.

PLoS Biol · 2025 · PMC12490766 · PMID 41037475

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While these results are distinct from ipsilateral results, ipsilateral cKO data did exhibit these trends (less frequent wake bouts, shorter REM bouts, and longer wake bouts) but the comparisons did not reach statistical significance as measured by a one-sided Wilcoxon rank-sum test (compare Figs 8C and S7C ; Figs 8D and S7D ).

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