Preclinical models of melanoma leptomeningeal disease to assess intrathecal checkpoint blockade.

Sci Rep · 2025 · PMC12491558 · PMID 41038921

Europe PMC DOI

hedged sentence

0.0720

closest p · 1.4× alpha

0.0720

boldest claim

The sentences

showed a trendp = 0.072so close (0.05 < p ≤ 0.1)

IP anti-PD1 alone also showed a trend for improved overall survival (HR = 0.346, p = 0.072), with 33.3% of mice surviving more than 28 days, and 10.0% of mice surviving > 6 months.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.