Barely Significant
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Individual patient data meta-analysis of placebo-controlled trials of selective serotonin reuptake inhibitors submitted for regulatory approval in adult obsessive-compulsive disorder.

Br J Psychiatry · 2025 · PMC12492065 · PMID 40369939

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A post hoc meta-regression comparing outcomes between obsessions and compulsions shows an estimate of –0.46 YBOCS points (95% CI −0.92 to 0.0042, p = 0.052), indicating a trend towards greater improvement in obsessions, although it did not reach statistical significance.

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