Brain network dynamics during rumination relate to relapse of depression.

Neuroimage Clin · 2025 · PMC12492253 · PMID 40987114

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nominally significantno p-value reported

Nominally significant findings ( P uncorrected < 0.05) with 0.05 ≤ P FDR < 0.1 were also reported as exploratory. 2.4.2 Correlation with rumination traits We explored associations between metrics showing significant differences in the rumination-distraction comparison and rumination traits.

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marginal significanceno p-value reported

Univariate logistic regression revealed that Reflection (OR = 1.3, 95 % CI: 1.1–1.7, P FDR = 0.038; n tests = 3) and Depression (OR = 1.1, 95 % CI: 1.0–1.2, P FDR = 0.038; n tests = 3) were significantly related to relapse, with Brooding showing marginal significance (OR = 1.2, 95 % CI: 1.0–1.4, P uncorrected = 0.071, P FDR = 0.071; n tests = 3).

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