In longer-term experiments, IVT devices showed a trend for continued IOP lowering; while this was not statistically significant at the final 16-week timepoint, average IOP in study eyes was numerically lower than controls at all timepoints following treatment, and this was statistically significant as late as 13 weeks and at 2 out of 8 timepoints from weeks 9 to 16.
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In Vivo Comparison of Intracameral and Intravitreal Implantation of a Timolol Maleate Miniaturized Injectable Delivery System Device.
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