Disruptions of p11 (S100A10) and HPA Axis Homeostasis Participate in the Major Depressive Disorder (MDD) Especially in Female Patients.

The underlying reasons for this are likely multifactorial: first, although some indicators (such as the p11 of CD4+/CD8+ T cell) showed a tendency toward elevation in the abnormal ACTH group during subgroup analysis, the differences did not reach statistical significance, likely due to the reduced sample size after stratification.

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