PLK1 inhibition enhances gemcitabine-induced apoptosis through PLK1-dependent ERK1/2-Bim and AKT1/Noxa signals in pancreatic cancer cells.

Med Oncol · 2025 · PMC12496299 · PMID 41045302

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did not reach statistical significanceno p-value reported

GEM led to a increase of a small amount of PLK1 expression in PANC-1 from 5 min to 3 h, but did not reach statistical significance (Fig. 6 A).

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