FRA1 (<i>FOSL1</i>) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks.

FRA1 levels were significantly reduced by approximately 70% in CGL1 FRA1KO#1 and 60% in CGL1 FRA1KO#3 compared to control cells (p < 0.05, n = 3), while CGL1 FRA1KO#2 showed a reduction that did not reach statistical significance ( Figure 1A ).

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