In addition, the co-culture of CD8 + T and NK cells showed a trend of decreased surface expression of NKG2D ligands, specifically MULT-1 and H60 on gated CD8 + T or NK cells ( Supplementary Figure S10 , Supplementary Table S6 ).
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CD8<sup>+</sup> T-NK cell crosstalk establishes preemptive immunosurveillance to eliminate antigen-escape tumors.
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