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A Machine-Learning Approach Identifies Rejuvenating Interventions in the Human Brain.

Adv Sci (Weinh) · 2025 · PMC12499397 · PMID 40660726

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showed a trendno p-value reported
2.5 Drugs Predicted by Our Clock to Rejuvenate the Transcriptome Reduced Anxiety in Older Mice and Showed a Trend Toward Improved Memory Performance Among the brain‐rejuvenating interventions that were individually predicted by our clock, an interesting subset includes 5‐azacytidine, tranylcypromine, and JNK‐IN‐5A (TCS JNK 5a), which influence epigenetic regulation.

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