highly significantP <0.0005
However, at subsequent time points, highly significant differences ( P <0.0005) in total body weight and fat mass were evident for both sexes, further confirming the impact of the HFD on body composition.
However, at subsequent time points, highly significant differences ( P <0.0005) in total body weight and fat mass were evident for both sexes, further confirming the impact of the HFD on body composition.
While these observations did not reach statistical significance, they imply that obesity may subtly alter early virus dissemination, particularly to the central nervous system, in a sex-dependent manner.