Real-World Outcomes of Baricitinib Monotherapy Versus csDMARD Combination Therapy in Rheumatoid Arthritis: A SingleCenter Retrospective Analysis of Efficacy, Safety, and Drug Retention.

All covariates that were statistically significant ( P < .05) or borderline significant ( P < .1 and > .05) in the bivariate analysis and those considered to be clinically significant were included in the multivariate Cox regression analysis by backward elimination of the variables.

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Although discontinuation due to AEs and overall treatment discontinuation were more frequent in the combination group, these differences did not reach statistical significance. This study found no significant difference in drug survival between BARI monotherapy and combination therapy groups (long rank test = 0.116) ( Figure 1 ).

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