Tumor Mutational Burden as a Prognostic Biomarker for Relapse-Free Survival in Hepatocellular Carcinoma: Insights from Long-Term Follow-Up.

Liver Cancer · 2025 · PMC12503890 · PMID 41063736

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0610

boldest claim

The sentences

showed a trendp = 0.055so close (0.05 < p ≤ 0.1)

Although not statistically significant, the TMB-high group showed a trend toward a higher frequency of intrahepatic tumor recurrence (52.6% vs. 27.1%, p = 0.055).

also in 53,322 other papers

a notable trendp = 0.061so close (0.05 < p ≤ 0.1)

However, the TMB-high group demonstrated a notable trend toward a higher frequency of microscopic hepatic vein invasion than the TMB-low group (24.4% vs. 12.6%, p = 0.061).

also in 2,380 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.