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Deficient DNA mismatch repair and Nectin-4 expression in upper tract urothelial carcinoma (UTUC).

J Cancer Res Clin Oncol · 2025 · PMC12504161 · PMID 41055665

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Notably, we contribute the discovery that MSH6 deficiency exhibited a statistically significant association with elevated Nectin-4 expression levels ( P = 0.013), whereas MSH2 deficiency similarly showed elevated expression trends that did not reach statistical significance.

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