We observed that day 1 adult clh-1 mutants showed a trend toward increased nuclear localization of DAF-16 compared to WT, a difference that was markedly enhanced by treatment with 50 mM paraquat ( Fig. 2, B and C ).
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The loss of a ClC anion channel increases life span, health span, and stress resistance by alkalinizing a pair of glial cells in <i>C. elegans</i>.
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