Real-world outcomes of immune checkpoint inhibitor-based combination therapy in older adult patients with metastatic renal cell carcinoma: a multi-center, retrospective analysis.

Front Immunol · 2025 · PMC12507601 · PMID 41080573

Europe PMC DOI

hedged sentence

0.1900

closest p · 3.8× alpha

0.1900

boldest claim

The sentences

did not reach statistical significancep=0.19not close (p > 0.1)

A similar trend was observed in older patients, although the association did not reach statistical significance in either the IO+IO (HR: 0.39, 95% CI: 0.09–1.67, p=0.19, Figure 4A ) or IO+TKI groups (HR: 0.52, 95% CI: 0.13–2.10, p=0.36, Figure 4B ). 4.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.