Neonatal intermittent hypoxemia events are associated with later systemic hypertension.

The relationship between IH events at 15–21 days of age and HTN or SBP did not reach statistical significance.

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These data may be significant in the context of the results of the present study since preterm infants with a greater number of apneic episodes exhibited an augmented hypoxic ventilatory response, which is suggestive of enhanced peripheral chemoreceptor activity. 46 These findings suggest potential multifactorial mechanisms by which IH may potentiate HTN.

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