Role for NF-κB in herpes encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity.

J Exp Med · 2026 · PMC12510166 · PMID 41065760

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did not reach statistical significanceno p-value reported

When monitoring for survival, we observed that Irf3 R278Q/R278Q mice showed significantly increased risk of death after HSV-1 infection, while the same tendency for the heterozygous Irf3 WT/R278Q mice did not reach statistical significance ( Fig. 1 L ).

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