Barely Significant
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A genome-wide association study identified 10 novel genomic loci associated with intrinsic capacity.

J Gerontol A Biol Sci Med Sci · 2025 · PMC12510315 · PMID 41066301

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nominally significantno p-value reported
Among these nominally significant pathways include the cell cycle, synaptic vesicle trafficking, mRNA splicing, Alzheimer's disease-presenilin pathway, coenzyme A biosynthesis, ubiquitin-proteasome pathway, transcriptional regulation by RUNX1, programmed cell death/apoptosis, class B/2 (secretin family receptors), TCF-dependent signaling in response to WNT, C-type lectin receptors (CLRs), DC42 GTPase cycle, and RAC1 GTPase cycle ( Figure 4 and Table S6 ).

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