Meta-evolutionary exome analysis identifies novel type 2 diabetes mellitus genes in the UK Biobank and all of us.

PLoS Genet · 2025 · PMC12510657 · PMID 41026804

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nominally significantno p-value reported

Taken together, these data demonstrate that MEVA identifies a robust set of candidates with the highest biological relevance, and that this signal of cross-cohort consistency extends to a wider group of nominally significant genes.

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highly significantno p-value reported

While the replication of 23 genes was highly significant, the incomplete overlap warrants examination.

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