Acrylamide-mediated errors in the cell cycle regulation are associated with altered TORC2 signaling in Schizosaccharomyces pombe.

Cells exposed to AA displayed a significant decrease in the expression of tor1 , ste20 , bit61 , and wat1 genes, while the decrease of the sin1 gene expression did not reach statistical significance (Fig. 7 A-E).

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Correlation analysis confirmed highly significant positive correlations between increased expression of genes involved in the antioxidant cascade (except for gst1 ) and production of total and individual ROS (Supplementary Fig. 3).

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