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Comparative analysis of PD-L1 expression and tumor-infiltrating lymphocytes between primary breast cancer and matched metastatic lesions: implications for immunotherapy.

Cent Eur J Immunol · 2025 · PMC12512122 · PMID 41079382

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While differences in PD-L1 expression were observed across molecular subtypes, correlations with clinical stage ( p = 0.096), multifocal disease ( p = 0.256), age ( p = 0.212), tumor size ( p = 0.232), and CD8/FoxP3 ratio ( p = 0.13) did not reach statistical significance.

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