Understanding organ donation refusal in the next of kin: a fifteen-year retrospective study in ten thousand potential donors.

However, Pearson’s correlation analysis revealed only a weak positive association between ICU volume and refusal rate ( r = 0.177; 95% CI: –0.002 to 0.345; p = 0.053), which did not reach statistical significance.

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We also addressed potential intra-country barriers, revealing significant regional differences in authorization to organ donation within the Italian population, with an increasing trend of refusal from northern (23%) to southern Italy (34%).

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