Perivascular inflammation in the progression of aortic aneurysms in Marfan syndrome.

Additionally, pitavastatin exhibited a trend toward suppression of inflammation in the perivascular tissues of NC-fed Fbn1 C1041G/+ mice, as evidenced by reduced accumulation of F4/80 + cells and decreased mRNA and protein expression levels of inflammatory cytokines, although these differences did not reach statistical significance ( Supplemental Figure 2 ).

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