Heart rate (HR) showed a small trend to increase with nitrate treatment, and ejection fraction and cardiac output were significantly elevated in the nitrate group, while there was a neutral effect on stroke volume of mice with HFrEF post TAC (Figure S1G–J ). 2.2.2.
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Dietary Nitrate Prevents Cardiac Dysfunction in HFrEF by Improving Hemodynamics, Ameliorating Remodeling, and Resolving Inflammation.
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Left ventricular systolic dimension (LVs) was significantly reduced and the diastolic dimension (LVD) showed a trend toward being lower in the nitrate group (Figure 1D,E ).