Relationship Between Phenotyping and Individualized Absolute Risk Differences in Sepsis: A Secondary Analysis of Two Approaches in Two Multicenter Trials.

Crit Care Explor · 2025 · PMC12520220 · PMID 41098209

Europe PMC DOI

hedged sentence

0.1400

closest p · 2.8× alpha

0.1400

boldest claim

The sentences

did not reach statistical significancep = 0.14not close (p > 0.1)

EGDT did not significantly reduce mortality in any clinical subtype in the combined cohort, and treatment by subtype interaction in response to EGDT did not reach statistical significance ( p = 0.14; Table 2 for mortality; and eTable 5 [ https://links.lww.com/CCX/B563 ] for patient characteristics by treatment arm).

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