We further validated this finding using the TCGA database (version 2024-08-05); however, due to the limited number of cases, the difference in HLF expression between triple- and double-mutated patients did not reach statistical significance (P = 0.401, S5 Table , S1 Fig ).
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HLF gene is a poor prognostic factor in acute myeloid leukemia patients with FLT3-ITD/NPM1 mutations undergoing hematopoietic transplantation.
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