Firmicutes was the phylum most frequently associated with T2DM, reported in all 14 studies, and consistently showed an increasing trend.
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Advances in the study of oral microbiota in association with T2DM: a systematic review.
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gingivalis) also showed a trend of increased abundance in several studies ( Gu et al., 2024 ).
Proteobacteria were mentioned in five studies, with most reporting a decreasing trend ( Cortelli et al., 2014 ; Kampoo et al., 2014 ; Shi et al., 2020 ; Guo et al., 2023 ; Tang et al., 2025 ).