Barely Significant
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A Comparative Study of Clinical, Hematological, and Biochemical Profiles in Eosinophilic and Non-eosinophilic Phenotypes of Chronic Obstructive Pulmonary Disease (COPD) During Acute Exacerbations.

Cureus · 2025 · PMC12521815 · PMID 41103838

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Although respiratory failure, bilevel positive airway pressure requirement, and mortality rates were numerically higher in non-eosinophilic patients, these differences did not reach statistical significance, though the trends suggest a more severe disease course in non-eosinophilic COPD.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.