nominally significantP < 0.05
Three of these proteins were nominally significant ( P < 0.05) and consistent with the direction of effect in the discovery cohort (SFTPB, effect size = 2.35, P = 1.4 × 10 –4 , BPI Fold Containing Family B Member 1 (BPIFB1), effect size = 1.90, P = 0.0075; PPIA, effect size = − 0.79, P = 0.0074; Fig. 1 C).