Barely Significant
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Real-World Effectiveness of Cisplatin, 5-Fluorouracil, and Pembrolizumab Combination Therapy for Unresectable or Recurrent Esophageal Cancer.

Cancers (Basel) · 2025 · PMC12523764 · PMID 41097729

1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)
Although not statistically significant, patients with recurrent disease showed a trend toward longer OS and PFS than those with unresectable disease (OS, p = 0.06; PFS, p = 0.05) ( Figure 2 ).

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